ZNF274

Across TCGA patient cohorts, ZNF274 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,823 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF274-associated proteins across cancer lineages are SDF2L1, SDF4, and ZSCAN18. Each is linked with ZNF274 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF274-to-partner and partner-to-ZNF274 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF274 versus SDF2L1 in CCRCC, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF274→partner) and Y-score (partner→ZNF274) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SDF2L1 →	-0.442	-0.437	<.001	.004	3	4
LUAD	SDF4 →	-0.372	-0.466	<.001	<.001	3	4
GBM	ZSCAN18 →	+0.652	+0.592	<.001	<.001	3	4
BRCA	UCK1 →	+0.259	+0.518	.002	.007	3	4
LUAD	RRBP1 →	-0.348	-0.463	<.001	<.001	3	4
OV	PPIF →	-0.622	-0.528	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,823 associations by consensus.

ZNF274 vs SDF2L1 — CCRCC

Explore this scatter interactively →