Across TCGA cell cohorts, ZNF273 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,136 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF273-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, DNA replication, and Mitotic cell cycle checkpoint signaling. Each is linked with ZNF273 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF273-to-partner and partner-to-ZNF273 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF273→partner) and Y-score (partner→ZNF273) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.136	+0.962	<.001	<.001	3	16
PANCREAS	DNA replication →	+0.117	+0.788	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Mitotic cell cycle checkpoint signaling →	+0.088	+0.825	.004	.003	3	15
PANCREAS	DNA-templated DNA replication →	+0.126	+0.760	<.001	<.001	3	14
PANCREAS	Cell cycle checkpoint signaling →	+0.079	+0.706	<.001	.002	3	14
OESOPHAGUS	Meiotic cell cycle process →	+0.074	+0.930	.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,136 associations by consensus.

Exploration

ZNF273 survival (RNA) · tumor vs normal (RNA) · all ZNF273 data types