Across TCGA cell cohorts, ZNF273 mutation is significantly associated with the mutation status of many other genes, with 3,701 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF273-associated genes across cancer lineages are CD3E, KDM2B, and VCAN. Each is linked with ZNF273 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF273-to-partner and partner-to-ZNF273 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF273→partner) and Y-score (partner→ZNF273) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CD3E →	+5.247	+4.429	.005	.005	1	3
LARGE_INTESTINE	KDM2B →	+1.777	+2.963	.004	.004	1	3
BLOOD_Lymphoma	VCAN →	+3.025	+3.754	.006	.006	1	3
LARGE_INTESTINE	COBLL1 →	+2.125	+3.278	.001	.001	1	3
BLOOD_Lymphoma	IWS1 →	+5.247	+4.429	.005	.005	1	3
LARGE_INTESTINE	ARMCX3 →	+4.807	+5.614	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,701 associations by consensus.

Exploration

ZNF273 survival (RNA) · tumor vs normal (RNA) · all ZNF273 data types