ZNF268

Across TCGA cell cohorts, ZNF268 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,549 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZNF268-associated GO terms across cancer lineages are DNA-templated transcription initiation, Protein-DNA complex organization, and Regulation of nucleotide-excision repair. Each is linked with ZNF268 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF268-to-partner and partner-to-ZNF268 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by ZNF268-low versus ZNF268-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF268→partner) and Y-score (partner→ZNF268) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DNA-templated transcription initiation →	+0.060	+0.867	<.001	.002	3	14
KIDNEY	Protein-DNA complex organization →	+0.056	+0.708	<.001	<.001	3	14
BREAST	Regulation of nucleotide-excision repair →	+0.104	+0.869	<.001	<.001	3	13
CNS	Nucleocytoplasmic transport →	+0.052	+0.515	<.001	.001	3	13
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.052	+0.515	<.001	.003	3	12
BREAST	Mitotic G2/M transition checkpoint →	+0.069	+0.713	.007	.003	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,549 associations by consensus.

DNA-templated transcription initiation by ZNF268 expression — LARGE_INTESTINE

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