ZNF267

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ZNF267 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZNF267 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ZNF267 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF267 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

PDAC, GBM, and LSCC are the cancer types where ZNF267 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACOSMedianAll0.7631.000.00324view →
GBMDFSQuartileAll0.6030.901.0305view →
LSCCOSMedianIII,IV0.9280.523.0353view →
HNSCDFSMedianIV0.7710.517.0381view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration