ZNF266

Across TCGA patient cohorts, ZNF266 mutation is significantly associated with the RNA expression of many other genes, with 2,228 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF266-associated genes across cancer lineages are RNU6-1305P, RNU6-18P, and FANCG. Each is linked with ZNF266 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF266-to-partner and partner-to-ZNF266 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1305P grouped by ZNF266-low versus ZNF266-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF266→partner) and Y-score (partner→ZNF266) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-1305P →	+0.186	+4.327	<.001	.009	3	3
HNSC	RNU6-18P →	+0.196	+4.883	<.001	.004	3	3
UCEC	FANCG →	+0.641	+2.673	<.001	<.001	3	3
BLCA	LINC01853 →	+0.453	+5.899	<.001	.002	3	3
COAD	RPS3AP9 →	+0.109	+2.992	<.001	.006	3	3
SKCM	RPL35P8 →	+0.136	+2.518	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,228 associations by consensus.

RNU6-1305P by ZNF266 expression — HNSC

Explore this box plot interactively →