ZNF266

Across TCGA cell cohorts, ZNF266 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,325 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZNF266-associated GO terms across cancer lineages are Microtubule nucleation, Microtubule polymerization, and mRNA splice site recognition. Each is linked with ZNF266 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF266-to-partner and partner-to-ZNF266 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule nucleation grouped by ZNF266-low versus ZNF266-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF266→partner) and Y-score (partner→ZNF266) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Microtubule nucleation →	+0.097	+0.807	<.001	.001	3	11
BLOOD_Leukemia	Microtubule polymerization →	+0.084	+0.734	.001	.003	3	10
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.115	+0.927	<.001	<.001	3	9
LUNG_SCLC	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.149	+1.073	<.001	<.001	3	8
BLOOD_Leukemia	Microtubule polymerization or depolymerization →	+0.076	+0.666	.002	.008	3	8
UPPER_AERODIGESTIVE_TRACT	mRNA 5'-splice site recognition →	+0.122	+0.795	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,325 associations by consensus.

Microtubule nucleation by ZNF266 expression — BLOOD_Leukemia

Explore this box plot interactively →