ZNF264

Across TCGA patient cohorts, ZNF264 mutation is significantly associated with the RNA expression of many other genes, with 3,718 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF264-associated genes across cancer lineages are NKG7, CRTAM, and RN7SL252P. Each is linked with ZNF264 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF264-to-partner and partner-to-ZNF264 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NKG7 grouped by ZNF264-low versus ZNF264-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF264→partner) and Y-score (partner→ZNF264) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NKG7 →	+1.325	+2.642	<.001	<.001	3	3
UCEC	CRTAM →	+0.495	+2.642	<.001	<.001	3	3
LUAD	RN7SL252P →	+0.097	+3.656	.005	.006	3	3
UCEC	SLAMF8 →	+0.818	+1.807	<.001	<.001	3	3
UCEC	MCM6 →	+0.656	+3.321	<.001	<.001	3	3
UCEC	LILRB4 →	+0.707	+2.269	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,718 associations by consensus.

NKG7 by ZNF264 expression — UCEC

Explore this box plot interactively →