ZNF264

Across TCGA cell cohorts, ZNF264 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF264-associated genes across cancer lineages are LYZL2, CRYGD, and MYL3. Each is linked with ZNF264 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF264-to-partner and partner-to-ZNF264 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LYZL2 grouped by ZNF264-low versus ZNF264-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF264→partner) and Y-score (partner→ZNF264) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	LYZL2 →	+0.016	+4.058	<.001	.007	3	2
LUNG_SCLC	CRYGD →	+0.679	+3.817	.002	.004	3	1
LUNG_SCLC	MYL3 →	+0.518	+4.070	<.001	.003	3	1
LUNG_SCLC	OR51Q1 →	+0.099	+3.662	.008	.009	3	1
LUNG_SCLC	DDI1 →	+0.034	+3.847	.005	.005	3	1
LUNG_SCLC	C12orf40 →	+0.028	+3.736	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

LYZL2 by ZNF264 expression — LUNG_SCLC

Explore this box plot interactively →