ZNF263

Across TCGA patient cohorts, ZNF263 mutation is significantly associated with the RNA expression of many other genes, with 1,058 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF263-associated genes across cancer lineages are TTTY9B, PTGES3P5, and OR8A3P. Each is linked with ZNF263 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF263-to-partner and partner-to-ZNF263 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTTY9B grouped by ZNF263-low versus ZNF263-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF263→partner) and Y-score (partner→ZNF263) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	TTTY9B →	+0.008	+4.040	<.001	.007	3	3
BRCA	PTGES3P5 →	+0.097	+6.064	<.001	.002	3	2
BLCA	OR8A3P →	+0.144	+3.826	<.001	<.001	3	2
BLCA	RNU6-87P →	+0.533	+2.850	<.001	.002	3	2
BLCA	RNU6-961P →	+0.122	+4.040	<.001	.007	3	2
SKCM	LINC02075 →	+0.083	+3.945	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,058 associations by consensus.

TTTY9B by ZNF263 expression — BLCA

Explore this box plot interactively →