ZNF263

Across TCGA cell cohorts, ZNF263 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,441 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF263-associated GO terms across cancer lineages are CAMP/PKA signal transduction, Regulation of chromatin organization, and Regulation of nucleotide-excision repair. Each is linked with ZNF263 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF263-to-partner and partner-to-ZNF263 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAMP/PKA signal transduction grouped by ZNF263-low versus ZNF263-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF263→partner) and Y-score (partner→ZNF263) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CAMP/PKA signal transduction →	+0.175	+0.670	<.001	<.001	3	16
BONE	Regulation of chromatin organization →	+0.128	+0.812	<.001	<.001	3	16
BONE	Regulation of nucleotide-excision repair →	+0.133	+0.742	<.001	.001	3	16
BREAST	Symbiont-mediated disruption of host cell PML body →	+0.097	+0.774	<.001	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.177	+0.891	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Regulation of cellular response to heat →	+0.096	+0.519	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,441 associations by consensus.

CAMP/PKA signal transduction by ZNF263 expression — SOFT_TISSUE

Explore this box plot interactively →