ZNF263

Across TCGA cell cohorts, ZNF263 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF263-associated genes across cancer lineages are OR8B4, OR6C68, and C8B. Each is linked with ZNF263 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF263-to-partner and partner-to-ZNF263 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B4 grouped by ZNF263-low versus ZNF263-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF263→partner) and Y-score (partner→ZNF263) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR8B4 →	+0.053	+5.087	<.001	.004	3	1
SKIN	OR6C68 →	+0.031	+4.415	<.001	.007	3	1
SKIN	C8B →	+0.063	+4.467	<.001	.004	3	1
LARGE_INTESTINE	AVP →	+0.056	+3.632	<.001	.003	3	1
LARGE_INTESTINE	OR10Q1 →	+0.106	+4.242	<.001	.001	3	1
LARGE_INTESTINE	FAM205A →	+0.020	+3.614	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR8B4 by ZNF263 expression — URINARY_TRACT

Explore this box plot interactively →