Across TCGA pan-cancer cohorts, ZNF259P1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZNF259P1 data layer compared with 17 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher ZNF259P1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF259P1 expression acts as an unfavorable survival marker.

OV and BRCA are the cancer types where ZNF259P1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.330	0.843	.002	18	view →
BRCA	OS	Median	All	0.148	0.578	.011	16	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: ZNF259P1 tumor-vs-normal RNA expression · all ZNF259P1 data types