Across TCGA cell cohorts, ZNF257 mutation is significantly associated with the RNA expression of many other genes, with 269 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF257-associated genes across cancer lineages are OR1L6, SLC10A2, and SLC22A24. Each is linked with ZNF257 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF257-to-partner and partner-to-ZNF257 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF257→partner) and Y-score (partner→ZNF257) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR1L6 →	+0.015	+4.807	<.001	.003	3	2
OESOPHAGUS	SLC10A2 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	SLC22A24 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	ZNF99 →	+0.023	+4.906	<.001	.006	3	1
BLOOD_Leukemia	IL4 →	+1.481	+4.007	.001	.002	3	1
BLOOD_Leukemia	SRY →	+0.018	+3.289	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 269 associations by consensus.

Exploration

ZNF257 survival (RNA) · tumor vs normal (RNA) · all ZNF257 data types