Across TCGA patient cohorts, ZNF254 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,031 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF254-associated proteins across cancer lineages are ARHGAP35, C5AR1_S327, and ELAVL1. Each is linked with ZNF254 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF254-to-partner and partner-to-ZNF254 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF254→partner) and Y-score (partner→ZNF254) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARHGAP35 →	+0.394	+0.790	<.001	<.001	3	4
COAD	C5AR1_S327 →	-1.098	-0.555	<.001	<.001	3	4
PDAC	ELAVL1 →	+0.346	+0.619	<.001	<.001	3	4
GBM	HDGFL2 →	+0.360	+0.565	<.001	<.001	3	4
GBM	HNRNPA3 →	+0.253	+0.555	<.001	<.001	3	4
GBM	PTPRJ →	-0.492	-0.765	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,031 associations by consensus.

Exploration

ZNF254 survival (RNA) · tumor vs normal (RNA) · all ZNF254 data types