Across TCGA cell cohorts, ZNF254 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,211 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF254-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Regulation of maintenance of sister chromatid cohesion, and Regulation of maintenance of mitotic sister chromatid cohesion. Each is linked with ZNF254 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF254-to-partner and partner-to-ZNF254 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF254→partner) and Y-score (partner→ZNF254) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.085	+1.156	<.001	<.001	3	9
SOFT_TISSUE	Regulation of maintenance of sister chromatid cohesion →	+0.121	+0.736	<.001	<.001	3	8
SOFT_TISSUE	Regulation of maintenance of mitotic sister chromatid cohesion →	+0.121	+0.736	<.001	<.001	3	8
BLOOD_Leukemia	RNA capping →	+0.091	+0.875	<.001	<.001	3	8
LUNG_SCLC	Peptidyl-lysine acetylation →	+0.123	+1.084	<.001	<.001	3	8
LUNG_SCLC	Protein acetylation →	+0.098	+1.065	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,211 associations by consensus.

Exploration

ZNF254 survival (RNA) · tumor vs normal (RNA) · all ZNF254 data types