Across TCGA cell cohorts, ZNF254 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZNF254-associated genes across cancer lineages are WFDC11, BANF2, and IL1F10. Each is linked with ZNF254 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF254-to-partner and partner-to-ZNF254 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF254→partner) and Y-score (partner→ZNF254) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	WFDC11 →	+0.046	+4.906	<.001	.006	3	2
BREAST	BANF2 →	+0.247	+3.672	<.001	.006	3	2
BLOOD_Myeloma	IL1F10 →	+0.036	+4.807	<.001	.006	3	1
BLOOD_Myeloma	TLE7 →	+0.006	+4.807	<.001	.006	3	1
OESOPHAGUS	MMP27 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	FSHR →	+0.013	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

ZNF254 survival (RNA) · tumor vs normal (RNA) · all ZNF254 data types