ZNF252P-AS1

Across TCGA pan-cancer cohorts, ZNF252P-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ZNF252P-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ZNF252P-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF252P-AS1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

HNSC, BLCA, and COAD are the cancer types where ZNF252P-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF252P-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.071	<.001	10	view →
BLCA	All	All	+0.376	<.001	9	view →
COAD	Male	II,III,IV	+0.364	<.001	9	view →
LIHC	Male	All	+0.296	<.001	9	view →
KIRC	Male	All	−0.115	<.001	8	view →
STAD	All	II,III,IV	+0.326	<.001	6	view →
BRCA	All	III,IV	+0.248	<.001	6	view →
CHOL	All	All	+0.862	<.001	5	view →
LUSC	Male	All	+0.261	<.001	5	view →
LUAD	Female	All	+0.253	<.001	5	view →
READ	All	All	+0.478	<.001	3	view →
PRAD	All	All	+0.217	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ZNF252P-AS1–HNSC

Open the HNSC breakdown →