Across TCGA patient cohorts, ZNF251 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,643 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF251-associated proteins across cancer lineages are SCRIB, NONO, and RBM12B. Each is linked with ZNF251 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF251-to-partner and partner-to-ZNF251 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF251→partner) and Y-score (partner→ZNF251) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SCRIB →	+0.470	+0.739	<.001	<.001	3	7
GBM	NONO →	+0.231	+0.420	<.001	<.001	3	6
BRCA	RBM12B →	+0.254	+0.556	.002	.001	2	7
GBM	TAF2 →	+0.267	+0.472	<.001	<.001	3	6
BRCA	DNAJC1 →	-0.582	-0.378	<.001	.006	3	6
LSCC	HNRNPR →	+0.271	+0.594	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,643 associations by consensus.

Exploration

ZNF251 survival (RNA) · tumor vs normal (RNA) · all ZNF251 data types