ZNF251

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF251 mutation is significantly associated with the RNA expression of many other genes, with 2,041 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF251-associated genes across cancer lineages are MIR2278, SKA1, and SEC13. Each is linked with ZNF251 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF251-to-partner and partner-to-ZNF251 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF251→partner) and Y-score (partner→ZNF251) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMIR2278 →+0.245+3.021<.001.00133
UCECSKA1 →+0.621+3.721<.001<.00132
UCECSEC13 →+0.386+1.939<.001.00832
UCECMED27 →+0.415+2.266<.001<.00132
UCECPEF1 →+0.320+3.893.001<.00132
UCECNDUFAF2 →+0.547+2.439<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,041 associations by consensus.

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