Across TCGA patient cohorts, ZNF250 mutation is significantly associated with the RNA expression of many other genes, with 834 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF250-associated genes across cancer lineages are RNY1P1, HMGN1P32, and MRPL49P2. Each is linked with ZNF250 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF250-to-partner and partner-to-ZNF250 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF250→partner) and Y-score (partner→ZNF250) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNY1P1 →	+0.154	+2.943	<.001	.001	3	3
PRAD	HMGN1P32 →	+0.196	+5.721	<.001	.003	3	2
BLCA	MRPL49P2 →	+0.142	+4.926	<.001	.002	3	2
BLCA	OSBPL9P3 →	+0.143	+5.618	<.001	.002	3	2
BLCA	RPA2P3 →	+0.090	+4.605	.001	.004	3	2
COAD	LINC01066 →	+0.163	+5.824	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 834 associations by consensus.

Exploration

ZNF250 survival (RNA) · tumor vs normal (RNA) · all ZNF250 data types