Across TCGA cell cohorts, ZNF250 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,685 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF250-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Regulation of nucleotide-excision repair, and Regulation of DNA-templated transcription initiation. Each is linked with ZNF250 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF250-to-partner and partner-to-ZNF250 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF250→partner) and Y-score (partner→ZNF250) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of double-strand break repair →	+0.086	+1.301	.001	<.001	3	12
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.119	+0.916	<.001	<.001	3	11
PANCREAS	Regulation of DNA-templated transcription initiation →	+0.072	+0.514	<.001	.009	2	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA repair →	+0.059	+0.731	.001	<.001	3	11
BONE	Positive regulation of DNA metabolic process →	+0.075	+0.806	.002	.003	3	11
LUNG_SCLC	Nucleosome organization →	+0.104	+0.916	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,685 associations by consensus.

Exploration

ZNF250 survival (RNA) · tumor vs normal (RNA) · all ZNF250 data types