Across TCGA cell cohorts, ZNF250 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF250-associated genes across cancer lineages are IL9, OOSP2, and OR10J5. Each is linked with ZNF250 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF250-to-partner and partner-to-ZNF250 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF250→partner) and Y-score (partner→ZNF250) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	IL9 →	+0.053	+5.781	<.001	.001	3	1
BREAST	OOSP2 →	+0.023	+5.781	<.001	.001	3	1
BREAST	OR10J5 →	+0.071	+5.169	<.001	.005	3	1
BREAST	OR2G6 →	+0.016	+5.169	<.001	.005	3	1
BREAST	OR10J1 →	+0.566	+5.781	<.001	.001	3	1
BLOOD_Lymphoma	KRTAP4-11 →	+0.045	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

ZNF250 survival (RNA) · tumor vs normal (RNA) · all ZNF250 data types