ZNF25

Across TCGA patient cohorts, ZNF25 protein abundance is significantly associated with the RNA expression of many other genes, with 5,586 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF25-associated genes across cancer lineages are COL3A1, COL1A1, and TGFB3. Each is linked with ZNF25 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF25-to-partner and partner-to-ZNF25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF25 versus COL3A1 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF25→partner) and Y-score (partner→ZNF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COL3A1 →	+1.852	+0.537	<.001	<.001	3	5
GBM	COL1A1 →	+1.926	+0.396	.002	.009	3	4
BRCA	TGFB3 →	+1.662	+0.777	<.001	<.001	3	4
BRCA	COL1A2 →	+1.942	+0.531	<.001	<.001	3	4
BRCA	NUAK1 →	+0.896	+0.404	<.001	.006	3	4
LSCC	LGALS1 →	+0.665	+0.326	.008	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,586 associations by consensus.

ZNF25 vs COL3A1 — BRCA

Explore this scatter interactively →