ZNF25

Across TCGA cell cohorts, ZNF25 protein abundance is significantly associated with the RNA expression of many other genes, with 2,370 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF25-associated genes across cancer lineages are ETV6, ADAM28, and KCNN4. Each is linked with ZNF25 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF25-to-partner and partner-to-ZNF25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF25 versus ETV6 in BLOOD_Lymphoma, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF25→partner) and Y-score (partner→ZNF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ETV6 →	+1.886	+1.431	.001	.001	3	6
SKIN	ADAM28 →	+0.675	+0.785	.009	.008	3	6
BLOOD_Leukemia	KCNN4 →	+2.285	+1.042	<.001	<.001	3	6
PANCREAS	TLR2 →	+1.808	+0.903	<.001	.002	3	5
OVARY	SECTM1 →	+2.682	+0.708	.003	.007	3	5
BLOOD_Leukemia	ANTXR2 →	+2.055	+1.084	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,370 associations by consensus.

ZNF25 vs ETV6 — BLOOD_Lymphoma

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