Across TCGA patient cohorts, ZNF248 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,689 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF248-associated proteins across cancer lineages are NUDT5, DOK3, and HDAC2. Each is linked with ZNF248 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF248-to-partner and partner-to-ZNF248 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF248→partner) and Y-score (partner→ZNF248) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NUDT5 →	+0.792	+0.731	<.001	.001	3	5
GBM	DOK3 →	-0.596	-0.504	<.001	.001	3	5
LSCC	HDAC2 →	+0.422	+0.578	<.001	<.001	3	5
GBM	TNFAIP8 →	-0.528	-0.396	<.001	<.001	3	4
LSCC	TOP2B →	+0.401	+0.484	<.001	<.001	3	4
GBM	PHC3 →	+0.373	+0.776	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,689 associations by consensus.

Exploration

ZNF248 survival (RNA) · tumor vs normal (RNA) · all ZNF248 data types