ZNF24

Across TCGA pan-cancer cohorts, ZNF24 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF24 data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher ZNF24 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF24 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

STAD, KIRC, and HNSC are the cancer types where ZNF24 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	All	0.112	0.657	<.001	30	view →
KIRC	OS	Median	All	0.170	0.811	.001	24	view →
HNSC	DFS	Median	II,III,IV	0.195	0.695	.030	12	view →
UCEC	DFS	Median	All	1.000	0.629	.027	6	view →
BRCA	OS	Median	All	0.191	0.579	.034	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF24–STAD (DFS)

Open the STAD breakdown →