ZNF24

Across TCGA pan-cancer cohorts, ZNF24 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF24 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ZNF24 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF24 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

COAD, LUAD, and PDAC are the cancer types where ZNF24 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
LUAD	OS	Quartile	All	0.647	0.895	.036	4	view →
PDAC	OS	Tertile	III,IV	0.459	0.847	.037	4	view →
LSCC	DFS	Median	All	0.822	0.626	.026	2	view →
CCRCC	DFS	Quartile	All	0.640	1.000	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF24–COAD (DFS)

Open the COAD breakdown →