Across TCGA patient cohorts, ZNF239 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF239-associated genes across cancer lineages are FoxM1, p62 Lck ligand, and 14-3-3_beta. Each is linked with ZNF239 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF239-to-partner and partner-to-ZNF239 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF239→partner) and Y-score (partner→ZNF239) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.241	+3.009	.032	.019	3	2
UCEC	p62 Lck ligand →	+0.294	+2.115	.038	.019	3	2
UCEC	14-3-3_beta →	-0.103	-3.143	.018	.018	3	1
UCEC	eEF2 →	+0.362	+3.169	.020	.019	3	1
UCEC	EGFR_pY1068 →	-0.294	-2.807	.007	.003	3	1
UCEC	ERK2 →	+0.246	+3.169	.003	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

ZNF239 survival (RNA) · tumor vs normal (RNA) · all ZNF239 data types