Across TCGA cell cohorts, ZNF239 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF239-associated genes across cancer lineages are CFC1B, PRORY, and SEMG2. Each is linked with ZNF239 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF239-to-partner and partner-to-ZNF239 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF239→partner) and Y-score (partner→ZNF239) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CFC1B →	+0.006	+5.781	<.001	.001	3	1
SKIN	PRORY →	+0.765	+4.009	<.001	<.001	3	1
LARGE_INTESTINE	SEMG2 →	+0.420	+2.878	.003	.009	3	1
LARGE_INTESTINE	SCGB2A1 →	+0.800	+3.392	<.001	.006	3	1
LARGE_INTESTINE	PLVAP →	+0.236	+3.539	<.001	.004	3	1
LARGE_INTESTINE	DEFA4 →	+0.022	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

ZNF239 survival (RNA) · tumor vs normal (RNA) · all ZNF239 data types