ZNF236

Across TCGA patient cohorts, ZNF236 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,533 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF236-associated proteins across cancer lineages are SMAD4, GATAD2B, and RPRD1A. Each is linked with ZNF236 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF236-to-partner and partner-to-ZNF236 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF236 versus SMAD4 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF236→partner) and Y-score (partner→ZNF236) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMAD4 →	+0.270	+0.322	<.001	<.001	3	8
GBM	GATAD2B →	+0.320	+0.333	<.001	<.001	3	6
LSCC	RPRD1A →	+0.419	+0.534	<.001	<.001	3	6
LSCC	RTF1 →	+0.358	+0.580	<.001	<.001	3	6
GBM	HCFC1 →	+0.214	+0.239	<.001	<.001	3	6
HNSC	HDAC2 →	+0.272	+0.398	.003	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,533 associations by consensus.

ZNF236 vs SMAD4 — GBM

Explore this scatter interactively →