ZNF236

Across TCGA patient cohorts, ZNF236 mutation is significantly associated with the RNA expression of many other genes, with 6,313 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF236-associated genes across cancer lineages are SAAL1, ZNHIT3, and RPL23AP82. Each is linked with ZNF236 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF236-to-partner and partner-to-ZNF236 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAAL1 grouped by ZNF236-low versus ZNF236-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF236→partner) and Y-score (partner→ZNF236) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	SAAL1 →	+0.684	+2.660	<.001	.004	3	5
STAD	ZNHIT3 →	+0.470	+3.824	<.001	<.001	3	4
SKCM	RPL23AP82 →	+0.412	+2.522	.006	.009	3	4
COAD	TRAPPC4 →	+0.424	+2.770	<.001	.002	3	4
COAD	PTMAP4 →	+1.363	+3.933	<.001	<.001	3	4
UCEC	TXN2 →	+0.390	+2.234	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,313 associations by consensus.

SAAL1 by ZNF236 expression — STAD

Explore this box plot interactively →