ZNF236

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF236 mutation is significantly associated with the RNA expression of many other genes, with 641 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF236-associated genes across cancer lineages are PATE1, KRTAP16-1, and CUEDC2. Each is linked with ZNF236 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF236-to-partner and partner-to-ZNF236 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PATE1 grouped by ZNF236-low versus ZNF236-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF236→partner) and Y-score (partner→ZNF236) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaPATE1 →+0.039+2.906<.001.00332
BLOOD_MyelomaKRTAP16-1 →+0.051+3.584.002.00232
LARGE_INTESTINECUEDC2 →+0.585+2.265<.001.00132
LARGE_INTESTINEPSMD9 →+0.426+2.459<.001.00632
LARGE_INTESTINETRIM62 →+0.425+3.321.005.00332
LARGE_INTESTINEPAIP2B →+0.563+2.067.009.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 641 associations by consensus.

PATE1 by ZNF236 expression — BLOOD_Myeloma

Box plot of PATE1 in ZNF236-low vs ZNF236-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration