ZNF236-DT

Across TCGA pan-cancer cohorts, ZNF236-DT RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ZNF236-DT data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZNF236-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF236-DT expression acts as an unfavorable survival marker, although some lineages such as UCEC and PAAD show a favorable association.

UCEC, PAAD, and LGG are the cancer types where ZNF236-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	0.857	0.638	<.001	92	view →
PAAD	OS	Median	All	0.543	0.261	<.001	70	view →
LGG	DFS	Median	All	0.652	0.821	<.001	54	view →
LIHC	OS	Quartile	II,III,IV	0.819	0.511	.003	42	view →
UVM	DFS	Tertile	All	0.306	0.674	.008	35	view →
READ	OS	Quartile	II,III,IV	0.456	0.806	.005	33	view →
KICH	OS	Median	III,IV	0.556	1.000	.010	27	view →
BLCA	DFS	Quartile	IV	0.107	0.350	.012	20	view →
CHOL	OS	Tertile	All	0.808	0.406	.009	18	view →
ESCA	DFS	Median	IV	0.634	0.205	.006	18	view →
OV	OS	Tertile	All	0.879	0.796	.009	16	view →
BRCA	OS	Median	IV	0.759	0.337	.008	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ZNF236-DT–UCEC (DFS)

Open the UCEC breakdown →