ZNF235

Across TCGA pan-cancer cohorts, ZNF235 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF235 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ZNF235 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF235 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

COAD, BLCA, and SKCM are the cancer types where ZNF235 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.236	0.695	<.001	28	view →
BLCA	OS	Median	All	0.253	0.721	.001	18	view →
SKCM	DFS	Median	II,III,IV	0.541	0.204	.008	13	view →
LIHC	OS	Median	All	0.144	0.688	.013	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF235–COAD (DFS)

Open the COAD breakdown →