ZNF234

Across TCGA patient cohorts, ZNF234 mutation is significantly associated with the RNA expression of many other genes, with 2,252 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF234-associated genes across cancer lineages are RNA5SP451, OR8B8, and ATXN3L. Each is linked with ZNF234 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF234-to-partner and partner-to-ZNF234 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP451 grouped by ZNF234-low versus ZNF234-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF234→partner) and Y-score (partner→ZNF234) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP451 →	+0.328	+8.055	<.001	.007	3	2
BLCA	OR8B8 →	+0.039	+4.899	<.001	.005	3	2
CESC	ATXN3L →	+0.015	+4.252	<.001	.006	3	2
CESC	OR5D17P →	+0.015	+4.579	<.001	.003	3	2
CESC	GAPDHP30 →	+0.032	+2.824	.003	.009	3	2
CESC	RNU6-33P →	+0.529	+3.700	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,252 associations by consensus.

RNA5SP451 by ZNF234 expression — BRCA

Explore this box plot interactively →