ZNF234

Across TCGA patient cohorts, ZNF234 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF234-associated genes across cancer lineages are ASNS, RAD51, and ATM. Each is linked with ZNF234 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF234-to-partner and partner-to-ZNF234 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZNF234-low versus ZNF234-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF234→partner) and Y-score (partner→ZNF234) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.527	+2.087	<.001	.005	3	3
UCEC	RAD51 →	+0.162	+2.807	<.001	.003	3	2
UCEC	ATM →	-0.524	-2.571	<.001	.010	3	2
UCEC	Caspase-7-cleavedD198 →	+0.565	+1.604	.005	.021	3	2
UCEC	4E-BP1 →	+0.352	+2.459	<.001	<.001	3	2
UCEC	EGFR_pY1068 →	-0.302	-3.807	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

ASNS by ZNF234 expression — UCEC

Explore this box plot interactively →