ZNF234

Across TCGA cell cohorts, ZNF234 mutation is significantly associated with the RNA expression of many other genes, with 147 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF234-associated genes across cancer lineages are GAGE12D, GAGE12C, and SH3GL2. Each is linked with ZNF234 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF234-to-partner and partner-to-ZNF234 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE12D grouped by ZNF234-low versus ZNF234-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF234→partner) and Y-score (partner→ZNF234) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	GAGE12D →	+0.712	+4.772	<.001	.002	3	1
CNS	GAGE12C →	+0.712	+4.772	<.001	.002	3	1
LARGE_INTESTINE	SH3GL2 →	+1.018	+3.474	.005	.003	3	1
LARGE_INTESTINE	FBXL4 →	+0.602	+3.212	<.001	.006	3	1
LARGE_INTESTINE	PCCB →	+0.730	+3.295	<.001	.003	3	1
LARGE_INTESTINE	RPF1 →	+0.740	+3.299	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 147 associations by consensus.

GAGE12D by ZNF234 expression — CNS

Explore this box plot interactively →