ZNF233

Across TCGA patient cohorts, ZNF233 mutation is significantly associated with the RNA expression of many other genes, with 1,638 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF233-associated genes across cancer lineages are RNU6-76P, SNRPGP13, and RNA5SP24. Each is linked with ZNF233 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF233-to-partner and partner-to-ZNF233 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-76P grouped by ZNF233-low versus ZNF233-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF233→partner) and Y-score (partner→ZNF233) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-76P →	+0.349	+9.057	<.001	.003	3	3
BLCA	SNRPGP13 →	+0.390	+5.329	<.001	.006	3	3
BRCA	RNA5SP24 →	+0.372	+7.731	<.001	.009	3	2
SKCM	ABALON →	+0.499	+3.341	.008	.005	3	2
HNSC	SPANXN4 →	+0.052	+4.696	<.001	<.001	3	2
HNSC	RN7SKP250 →	+0.095	+3.767	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,638 associations by consensus.

RNU6-76P by ZNF233 expression — BRCA

Explore this box plot interactively →