ZNF233

Across TCGA cell cohorts, ZNF233 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF233-associated genes across cancer lineages are HNRNPCL4, GOT1L1, and CGB8. Each is linked with ZNF233 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF233-to-partner and partner-to-ZNF233 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HNRNPCL4 grouped by ZNF233-low versus ZNF233-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF233→partner) and Y-score (partner→ZNF233) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HNRNPCL4 →	+0.064	+3.793	<.001	.007	3	2
BLOOD_Leukemia	GOT1L1 →	+0.060	+5.569	<.001	.001	3	1
BLOOD_Leukemia	CGB8 →	+0.081	+4.551	<.001	.004	3	1
SKIN	GYS2 →	+0.018	+4.467	<.001	.004	3	1
BLOOD_Leukemia	AKR1B15 →	+0.025	+4.191	.006	.007	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

HNRNPCL4 by ZNF233 expression — LARGE_INTESTINE

Explore this box plot interactively →