ZNF230

Across TCGA patient cohorts, ZNF230 mutation is significantly associated with the RNA expression of many other genes, with 2,324 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF230-associated genes across cancer lineages are NAE1, RPL23AP7, and RHOT1. Each is linked with ZNF230 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF230-to-partner and partner-to-ZNF230 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NAE1 grouped by ZNF230-low versus ZNF230-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF230→partner) and Y-score (partner→ZNF230) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NAE1 →	+0.546	+3.347	.006	.004	3	3
UCEC	RPL23AP7 →	+0.388	+2.070	.001	.001	3	3
LUSC	RHOT1 →	+0.576	+3.477	<.001	.002	3	3
UCEC	SLC7A6OS →	+0.490	+1.950	<.001	.002	3	3
UCEC	RAD51C →	+0.378	+1.747	.003	.004	3	3
SKCM	ADAL →	+0.517	+2.228	.008	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,324 associations by consensus.

NAE1 by ZNF230 expression — SKCM

Explore this box plot interactively →