ZNF230

Across TCGA cell cohorts, ZNF230 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF230-associated genes across cancer lineages are CFHR2 and PTH2R. Each is linked with ZNF230 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF230-to-partner and partner-to-ZNF230 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by ZNF230-low versus ZNF230-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF230→partner) and Y-score (partner→ZNF230) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CFHR2 →	+0.038	+4.022	<.001	.006	3	1
LARGE_INTESTINE	PTH2R →	+0.653	+3.453	.008	.009	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CFHR2 by ZNF230 expression — LARGE_INTESTINE

Explore this box plot interactively →