ZNF23

Across TCGA patient cohorts, ZNF23 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,446 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF23-associated proteins across cancer lineages are EDC4, TERF2, and IRF4. Each is linked with ZNF23 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF23-to-partner and partner-to-ZNF23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF23 versus EDC4 in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF23→partner) and Y-score (partner→ZNF23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EDC4 →	+0.267	+0.202	.001	.001	3	5
GBM	TERF2 →	+0.424	+0.316	<.001	<.001	3	4
LUAD	IRF4 →	-0.517	-0.169	.001	.002	3	4
GBM	SF3B3 →	+0.232	+0.330	<.001	<.001	3	4
BRCA	WWP2 →	+0.291	+0.164	.001	.003	3	4
OV	IST1 →	+0.224	+0.211	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,446 associations by consensus.

ZNF23 vs EDC4 — BRCA

Explore this scatter interactively →