ZNF23

Across TCGA cell cohorts, ZNF23 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,228 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ZNF23-associated GO terms across cancer lineages are Protein modification by small protein removal, RNA-templated DNA biosynthetic process, and Protein localization to nucleus. Each is linked with ZNF23 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF23-to-partner and partner-to-ZNF23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein modification by small protein removal grouped by ZNF23-low versus ZNF23-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF23→partner) and Y-score (partner→ZNF23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein modification by small protein removal →	+0.054	+0.543	<.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	RNA-templated DNA biosynthetic process →	+0.097	+0.508	.002	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein localization to nucleus →	+0.039	+0.551	.007	.002	3	10
BLOOD_Myeloma	Positive regulation of organelle assembly →	+0.059	+0.732	<.001	<.001	3	10
OVARY	Regulation of maintenance of sister chromatid cohesion →	+0.109	+0.771	<.001	.001	3	10
OVARY	Regulation of maintenance of mitotic sister chromatid cohesion →	+0.109	+0.771	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,228 associations by consensus.

Protein modification by small protein removal by ZNF23 expression — LUNG_SCLC

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