ZNF23

Across TCGA cell cohorts, ZNF23 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF23-associated genes across cancer lineages are TRIM51, OR10V1, and RFX4. Each is linked with ZNF23 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF23-to-partner and partner-to-ZNF23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM51 grouped by ZNF23-low versus ZNF23-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF23→partner) and Y-score (partner→ZNF23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TRIM51 →	+0.040	+4.152	.008	.009	3	2
OESOPHAGUS	OR10V1 →	+0.028	+4.017	.002	.007	3	1
URINARY_TRACT	RFX4 →	+0.018	+3.906	<.001	.009	3	1
URINARY_TRACT	OR2A14 →	+0.024	+4.050	<.001	.002	3	1
SOFT_TISSUE	SPANXN4 →	+0.946	+4.930	<.001	.008	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+3.678	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

TRIM51 by ZNF23 expression — BLOOD_Leukemia

Explore this box plot interactively →