ZNF227

Across TCGA patient cohorts, ZNF227 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,283 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF227-associated proteins across cancer lineages are UBA2, TRIM28, and SAE1. Each is linked with ZNF227 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF227-to-partner and partner-to-ZNF227 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF227 versus UBA2 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF227→partner) and Y-score (partner→ZNF227) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	UBA2 →	+0.340	+0.725	<.001	<.001	3	8
GBM	TRIM28 →	+0.440	+0.557	<.001	<.001	3	8
GBM	SAE1 →	+0.372	+0.537	<.001	<.001	3	8
GBM	PPP5C →	+0.329	+0.661	<.001	<.001	3	7
GBM	ZNF574 →	+0.443	+0.554	<.001	<.001	3	6
OV	S100A9 →	-1.282	-0.454	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,283 associations by consensus.

ZNF227 vs UBA2 — OV

Explore this scatter interactively →