ZNF225

Across TCGA patient cohorts, ZNF225 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,921 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF225-associated proteins across cancer lineages are PPIF, IRGQ, and PAFAH1B3. Each is linked with ZNF225 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF225-to-partner and partner-to-ZNF225 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF225 versus PPIF in HNSC, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF225→partner) and Y-score (partner→ZNF225) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PPIF →	-0.574	-0.531	<.001	.003	3	6
OV	IRGQ →	+0.285	+0.459	<.001	<.001	3	6
BRCA	PAFAH1B3 →	+0.461	+0.462	<.001	<.001	3	5
BRCA	FERMT2 →	+0.502	+0.411	<.001	.001	3	5
CCRCC	HTATIP2 →	-0.485	-0.234	<.001	<.001	3	5
LSCC	IRF2BP1_S66 →	+0.492	+0.364	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,921 associations by consensus.

ZNF225 vs PPIF — HNSC

Explore this scatter interactively →