ZNF225

Across TCGA patient cohorts, ZNF225 mutation is significantly associated with the RNA expression of many other genes, with 2,430 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF225-associated genes across cancer lineages are RN7SL447P, MIR1537, and NFU1P2. Each is linked with ZNF225 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF225-to-partner and partner-to-ZNF225 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL447P grouped by ZNF225-low versus ZNF225-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF225→partner) and Y-score (partner→ZNF225) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	RN7SL447P →	+0.357	+5.345	<.001	.005	3	3
SARC	MIR1537 →	+0.746	+6.152	<.001	.001	3	2
SARC	NFU1P2 →	+0.128	+5.005	<.001	.009	3	2
SKCM	RN7SKP126 →	+0.045	+3.897	<.001	.009	3	2
UCEC	HARS2 →	+0.413	+2.280	<.001	.001	3	2
UCEC	GTF3A →	+0.454	+3.435	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,430 associations by consensus.

RN7SL447P by ZNF225 expression — SARC

Explore this box plot interactively →