ZNF223

Across TCGA patient cohorts, ZNF223 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,489 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF223-associated proteins across cancer lineages are TRIM28, SASH3, and IRGQ. Each is linked with ZNF223 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF223-to-partner and partner-to-ZNF223 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF223 versus TRIM28 in GBM, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF223→partner) and Y-score (partner→ZNF223) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.446	+0.387	<.001	<.001	3	5
LSCC	SASH3 →	-0.368	-0.300	.002	.004	3	5
GBM	IRGQ →	+0.307	+0.370	<.001	<.001	3	5
CCRCC	TBX2_S360 →	+0.675	+0.283	<.001	<.001	3	4
GBM	PYCARD →	-0.503	-0.376	<.001	<.001	3	4
BRCA	RPL5 →	-0.261	-0.509	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,489 associations by consensus.

ZNF223 vs TRIM28 — GBM

Explore this scatter interactively →