ZNF223

Across TCGA patient cohorts, ZNF223 mutation is significantly associated with the RNA expression of many other genes, with 1,865 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF223-associated genes across cancer lineages are VEZF1P1, MTND4LP19, and RN7SL788P. Each is linked with ZNF223 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF223-to-partner and partner-to-ZNF223 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VEZF1P1 grouped by ZNF223-low versus ZNF223-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF223→partner) and Y-score (partner→ZNF223) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	VEZF1P1 →	+0.079	+3.917	.006	.002	3	3
LIHC	MTND4LP19 →	+0.210	+6.479	<.001	.001	3	2
LIHC	RN7SL788P →	+0.276	+5.355	<.001	.005	3	2
ESCA	SLC25A6P6 →	+0.352	+5.068	<.001	.008	3	2
ESCA	IFNWP4 →	+0.233	+5.450	<.001	.004	3	2
BRCA	LSM6P2 →	+0.181	+4.883	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,865 associations by consensus.

VEZF1P1 by ZNF223 expression — LUAD

Explore this box plot interactively →